Professor Tony Wilkes

• Evaluation of anaesthetic equipment as part of government-funded project (funded by DHSS Procurement Directorate, Medical Devices Directorate, Medical Devices Agency, Medicines and Healthcare products Regulatory Agency). More than 50 reports published in Evaluation series (1988 to 2004)
• Joint lead for two Buyers’ Guides for the Centre for Evidence-based Purchasing, part of the NHS Purchasing and Supply Agency
  • Laryngeal masks (CEP 08010, 2008)
  • Laryngoscopes (CEP 08048, 2009)
• Acting Director ofResearch, Department of Anaesthetics, Intensive Care and Pain Medicine at Cardiff University

Other positions of responsibility

• Consultant on medical devices for CEN (European Standards Committee) (2009 - )
• Honorary Statistical Advisor to Cedar, Cardiff and Vale University Local Health Board, carrying out projects for NICE (2014 - )
• Member of the Editorial Board of Respiratory Care (2013 and 2014)
• Joint lead on project for AAMI (Association for the Advancement of Medical Instrumentation) ‘Summative usability testing of the ISO 80369-6 small-bore connector foruse with ‘Neuraxial’ medical devices’ (2014)
• Training Officer on the Anaesthetic Research Society Council, responsible for organising the Research Methods Workshop(2007 to 2010)
• Member of the Working Party set up by the Association of Anaesthetists of Great Britain and Ireland (AAGBI) to update the guidance ‘Anaesthetic-related equipment. Purchase, maintenance and replacement’; the update was published by the AAGBI in 2009

Award

• Pask Certificate of Honour awarded by the Association of Anaesthetists of Great Britain and Ireland (2007)

Publications in peer-reviewed journals

1. Salama IE, Jenkins CL, Davies A, Clark JN, Wilkes AR, Hall JE, Paul A. Volatile fluorinated nanoemulsions: a chemical route to controlled delivery of inhalation anesthesia. Journal of Colloid and Interface Science 2015;440:78-83.
2. White J, Ivins N, Wilkes A, Carolan-Rees G, Harding KG. Non-contact low-frequency ultrasound therapy comparedwith UK standard of care for venous leg ulcers: asingle-centre, assessor-blinded, randomised controlled trial.International Wound Journal 2015; (published early on-line).
3. Szakmany T, Russell P, Wilkes AR, Hall JE.Effect of early tracheostomy on resource utilization and clinical outcomes in critically ill patients: meta-analysis of randomized controlled trials.British Journal of Anaesthesia 2014; (published early on-line).
4. Roberts MH, Boucher EK, Lim M, Wilkes AR, Hodzovic I. Evaluation of tip surface collision count asa measure of fibreopticscope handling skills: arandomized, cross-over manikin study. Journal of Anesthesiology2014, Article ID 718092.
5. Wilkes AR.Humidification in intensive care: are we there yet?Respiratory Care 2014; 59:790-3.
6. Marson BA, Anderson E, Wilkes AR, Hodzovic I. Bougie-related airway trauma: dangers of the hold-up sign. Anaesthesia 2014; 69: 219-23.
7. Jayakumar A, Ateleanu B, Wilkes AR, Hodzovic I. Effect of trolley height on the management of difficult airway; a manikin study. Romanian Journal of Anaesthesia and Intensive Care 2013; 20: 94-8.
8. Morton WJ, Muller CT, Goodwin N, Wilkes AR, Hall JE. Investigation of phthalate release from tracheal tubes. Anaesthesia 2013, 68: 377–81.
9. Richardson PB, Krishnan S, Janakiraman C, Wilkes AR, Hodzovic I. Extubation after anaesthesia: a randomised comparison of three techniques. ActaClinicaCroatica 2012; 51: 529-36.
10. Cook TM, Pandit J, Wilkes AR. Introduction and evaluation of new airway devices: current issues. Trends in Anaesthesia and Critical Care 2012; 2: 264-8.
11. HiomSJ, DenyerS, TalbotC, WilkesAR. Investigating rapid microbial detection methods as an alternative to total aerobic microbial counts for non-sterile bioburden assessments. European Journal of Parenteral and Pharmaceutical Sciences 2012; 17: 138-41.
12. Bell SF, Morris NG, Rao A, Wilkes AR, Goodwin N. A randomised crossover trial comparing a single-use polyvinyl chloride laryngeal mask with a single-use silicone laryngeal mask. Anaesthesia 2012; 67: 1337-42.
13. McPherson D, Vaughan RS, Wilkes AR, Mapleson WW, Hodzovic I. A survey of anaesthetic practice in predicting difficult intubation in UK and Europe. European Journal of Anaesthesiology 2012; 29: 218-22.
14. Sheraton TE, Wilkes AR, Hall JE. Mobile phones and the developing world. Anaesthesia 2012; 67: 945-50.
15. Richardson PB, Turner MW, Wilkes AR. Epidural catheter connectors: a laboratory-based comparison of the PortexTuohy-Borst and EpiFuseTM designs. Anaesthesia 2012; 67: 1119–24.
16. Vijayakumar M, Clarke A, Wilkes AR, Goodwin N, Hodzovic I. Comparison of the manoeuvrability and ease of use of the AmbuaScope and Olympus re-usable fibrescope in a manikin. Anaesthesia 2011; 66: 689-93.
17. Pandit JJ, Popat MT, Cook TM, Wilkes AR, Groom P, Cooke H, Kapila A, O’Sullivan E. The Difficult Airway Society ‘ADEPT’ Guidance on selecting airway devices: the basis of a strategy for equipment evaluation. Anaesthesia 2011; 66: 726-37.
18. Wilkes AR, Pandit JJ, O’Sullivan E. The history of anaesthetic equipment evaluation in the United Kingdom: lessons for developing future strategy. Anaesthesia 2011; 66(Suppl. 2): 34–9.
19. Dugani S, Hodzovic I, Sindhakar S, Nadra A, Dunstan C, Wilkes AR, Mecklenburgh J. Evaluation of a pulse oximeter sensor tester. Journal of Clinical Monitoring and Computing 2011; 25: 163–170.
20. Wilkes AR. Heat and moisture exchangers and breathing system filters: their use in anaesthesia and intensive care. Part 2 - practical use, including problems, and their use with paediatric patients. Anaesthesia 2011; 66: 40-51.
21. Wilkes AR. Heat and moisture exchangers and breathing system filters: their use in anaesthesia and intensive care. Part 1 – history, principles and efficiency. Anaesthesia 2011; 66: 31-39.
22. Coakley M, Hall JE, Evans C, Duff E, Billing V, Yang L, McPherson D, Stephens E, Macartney N, Wilkes AR, Collins PW. Assessment of thrombin generation measured before and after cardiopulmonary bypass surgery and its association with post-operative bleeding. Journal of Thrombosis and Haemostasis 2011; 9: 282-92.
23. Lewis AR, Hodzovic I, Whelan J, Wilkes AR, Bowler I, Whitfield R. A paramedic study comparing the use of the Airtraq(®) , Airway Scope and Macintosh laryngoscopes in simulated prehospital airway scenarios. Anaesthesia 2010; 65: 1187-93.
24. Cann C, Wilkes AR, Hall JE, Kumar RA. Are we using our brains? Diagnosis of postoperative cognitive dysfunction. Anaesthesia 2010; 65: 1166-9.
25. Kramer A, Kranabetter R, Rathgeber J, Züchner K, Assadian O, Daeschlein G, Hübner NO, Dietlein E, Exner M, Gründling M, Lehmann C, Wendt M, Graf BM, Holst D, Jatzwauk L, Puhlmann B, Welte T, Wilkes AR. Infection prevention during anaesthesia ventilation by the use of breathing system filters (BSF): joint recommendation by German Society of Hospital Hygiene (DGKH) and German Society for Anaesthesiology and Intensive Care (DGAI). GMS KrankenhaushygieneInterdisziplinär 2010; 5: 1-19.
26. Poonawala Y, Wilkes AR, Cann C, Hall JE. The effect of desflurane on filtration performance of breathing system filters. Anaesthesia 2010; 65: 831-5.
27. Dugani S, Kumar A, Wilkes AR. Influence of patient factors on the efficacy of breathing system filters at preventing contamination of breathing systems. Anaesthesia 2010; 65: 468-72.
28. de Lloyd L, Hodzovic I, Voisey S, Wilkes AR, Latto IP. Comparison of fibrescope guided intubation via the classic laryngeal mask airway and i-gel in a manikin. Anaesthesia 2010; 65: 36-43.
29. Hodzovic I, Janakiraman C, Sudhir G, Goodwin N, Wilkes AR, Latto IP. Fibreoptic intubation through the laryngeal mask airway: effect of operator experience. Anaesthesia 2009; 64: 1066–71.
30. Janakiraman C, Chethan DB, Wilkes AR, Stacey MR, Goodwin N. A randomised crossover trial comparing the i-gel supraglottic airway and classic laryngeal mask airway. Anaesthesia 2009; 64: 674-8.
31. Janakiraman C, Hodzovic I, Reddy S, Desai N, Wilkes AR, Latto IP. Evaluation of tracheal tube introducers in simulated difficult intubation. Anaesthesia 2009; 64: 309-14.
32. McPherson D, Adekanye O, Wilkes AR, Hall JE. Fluid flow through intravenous cannulae in a clinical model. Anesthesia and Analgesia 2009; 108: 1198-202.
33. Shylasree TS, Karanjgaokar V, Tristram A, Wilkes AR, MacLean AB, Fiander AN. Contribution of demographic, psychological and disease-related factors to quality of life in women with high-grade vulval intraepithelial neoplasia. Gynecologic Oncology 2008; 110: 185-9.
34. Wilkes AR, Hodzovic I, Latto IP. Introducing new anaesthetic equipment into clinical practice (Editorial). Anaesthesia 2008; 63: 571-5.
35. Hodzovic I, Wilkes AR, Stacey M, Latto IP. Evaluation of clinical effectiveness of the Frova single-use tracheal tube introducer. Anaesthesia 2008; 63: 189-94.
36. Froom SR, Cann C, Wilkes AR, Gildersleve C, Hall JE. The effect of volatile anaesthetic agents on the filtration performance of paediatric breathing system filters.Anaesthesia 2008; 63: 77-81.
37. Wilkes AR, Malan CA, Hall JE. The effect of flow on the filtration performance of paediatric breathing system filters. Anaesthesia 2008; 63: 71-6.
38. Malan CA, Scholz A, Wilkes AR, Hampson MA, Hall JE. Minimum and optimum light requirements for laryngoscopy in paediatricanaesthesia: a manikin study. Anaesthesia 2008; 63: 65-70.
39. HodzovicI,LattoIP, Pradhan P,Gururaj P,Wilkes A,Gataure P,Popat M. Effect of the provision of an airway training module on the acquisition of complex airway skills. Internet Journal of Anesthesiology 2007; 15(on-line publication).
40. Sudhir G, Wilkes AR, Clyburn P, Aguilera I, Hall JE. User satisfaction and forces generated during laryngoscopy using disposable Miller blades: a manikin study. Anaesthesia 2007; 62: 1056-60.
41. Sudhir G, Redfern D, Hall JE, Wilkes AR, Cann C. A comparison of the disposable AmbuAuraOnce laryngeal mask with the reusable LMA Classic laryngeal mask airway. Anaesthesia 2007; 62: 719-22.
42. Hodzovic I, Petterson J, Wilkes AR, Latto IP. Fibreoptic intubation using three airway conduits in a manikin: the effect of operator experience. Anaesthesia 2007; 62: 591-7.
43. Malan CA, Wilkes AR, Hall JE, Gildersleve C. An evaluation of the filtration performance of paediatric breathing system filters at low flows. Anaesthesia 2007; 62: 504-8.
44. Kumar RA, Cann C, Hall JE, Sudheer PS, Wilkes AR. Predictive value of IL-18 and SC5b-9 for neurocognitive dysfunction after cardiopulmonary bypass. British Journal of Anaesthesia 2007; 98: 317-22.
45. ScholzA, Farnum N, Wilkes AR, Hampson MA, Hall JE. Minimal and optimal light output of Macintosh size 3 laryngoscopy blades: a manikin study. Anaesthesia 2007; 62: 163-8.
46. Rees LM, Sheraton TE, Modestini C, Wilkes AR, Hall JE. Assessing the efficacy of HME filters at preventing contamination of breathing systems. Anaesthesia 2007; 62: 67-71.
47. Wilkes AR. Preface - Humidification and filtration in anesthesia and intensive care. Respiratory Care Clinics of North America 2006; 12: xiii-xv.
48. Goodwin N, Wilkes AR, Hall JE. Flexibility and light emission of disposable paediatric Miller 1 laryngoscope blades. Anaesthesia 2006; 61: 792-9.
49. Cann C, Hampson MA, Wilkes AR, Hall JE. The pressure required to force liquid through breathing system filters. Anaesthesia 2006; 61: 492-7.
50. King R, Bretland M, Wilkes A, Dingley J. Xenon measurements in breathing systems: a comparison of ultrasonic and thermal conductivity methods. Anaesthesia 2005; 60: 1226-30.
51. Goodwin N, Strong PJ, Sudhir G, Wilkes AR, Hall JE. Effect of breathing low concentrations of volatile anaesthetic agents on incidence of adverse airway events. Anaesthesia 2005; 60: 955-9.
52. Chawathe M, Zatman T, Hall JE, Gildersleve C, Jones RM, Wilkes AR, Aguilera IM, Armstrong TS. Sevoflurane (12% and 8%) inhalational induction in children. PediatricAnesthesia 2005; 15: 470-5.
53. Wilkes AR. Reducing the risk of the transmission of prions between patients in anaesthesia (Editorial). Anaesthesia 2005, 60: 527-9.
54. Rassam S, Wilkes AR, Hall JE, Mecklenburgh JS. A comparison of 20 laryngoscope blades using an intubating manikin: visual analogue scores and forces exerted during laryngoscopy. Anaesthesia 2005, 60: 384-94.
55. Hodzovic I, Latto IP, Wilkes AR, Hall JE, Mapleson WW. Evaluation of Frova, single-use intubation introducer, in a manikin. Comparison with Eschmann multiple-use introducer and Portex single-use introducer. Anaesthesia 2004; 59: 811-6.
56. Wilkes AR. The effect of gas flow on the filtration performance of breathing system filters. Anaesthesia 2004; 59: 278-82.
57. Wilkes AR. The moisture-conserving performance of breathing system filters in use with simulated circle anaesthesia breathing systems. Anaesthesia 2004; 59: 271-7.
58. Wilkes AR. The moisture-conserving performance of breathing system filters during the first three minutes of simulated use. Anaesthesia 2004; 59: 265-70.
59. Hodzovic I, Wilkes AR, Latto IP. Bougie-assisted difficult airway management in a manikin – the effect of position held on placement and force exerted by the tip. Anaesthesia 2004; 59: 38-43.
60. Evans A, Vaughan RS, Hall JE, Mecklenburgh J, Wilkes AR. A comparison of the forces exerted during laryngoscopy using disposable and non-disposable laryngoscope blades. Anaesthesia 2003; 58: 869-73.
61. Hodzovic I, Wilkes AR, Latto IP. To shape or not to shape … simulated bougie-assisted difficult intubation in a manikin. Anaesthesia 2003; 58: 791-7.
62. Wilkes AR. The effect of loading on the filtration performance of breathing system filters. Anaesthesia 2003; 58: 562-7.
63. Wilkes AR, Raj N, Hall JE. Adverse airway events during brief nasal inhalations of volatile anaesthetics: the effect of humidity and repeated exposure on incidence in volunteers preselected by response to desflurane. Anaesthesia 2003; 58: 207-16.
64. Annamaneni R, Hodzovic I, Wilkes AR, Latto IP. A comparison of simulated difficult intubation with multiple-use and single-use bougies in a manikin. Anaesthesia 2003; 58: 45-9.
65. Campbell AE, Turley A, Wilkes AR, Hall JE. Cricoid yoke: the effect of surface area and applied force on discomfort experienced by conscious volunteers. European Journal of Anaesthesiology 2003; 20: 52-5.
66. Wilkes AR. Comparison of two techniques for measuring penetration of sodium chloride particles through breathing system filters. British Journal of Anaesthesia 2002; 89: 541-5.
67. Wilkes AR. Breathing system filters. British Journal of Anaesthesia CEPD Reviews 2002; 2: 151-4.
68. Wilkes AR. Measuring the filtration performance of breathing system filters using sodium chloride particles. Anaesthesia 2002; 57: 162-8.
69. Wilkes AR. The ability of breathing system filters to prevent liquid contamination of breathing systems: a laboratory study. Anaesthesia 2002; 57: 33-9.
70. Wilkes AR. Humidification: its importance and delivery. British Journal of Anaesthesia CEPD Reviews 2001; 1: 40-3.
71. Wilkes AR, Hall JE, Wright E, Grundler S. The effect of humidification and smoking habit on the incidence of adverse airway events during deepening of anaesthesia with desflurane. Anaesthesia 2000; 55: 685-94.
72. Wilkes AR, Benbough JE, Speight SE, Harmer M. The bacterial and viral filtration performance of breathing system filters. Anaesthesia 2000; 55: 458-65.
73. Wilkes AR, Vaughan RS. The use of breathing system filters as oxygen-delivery devices. Anaesthesia 1999; 54: 552-8.
74. Wilkes AR. Heat and moisture exchangers. Structure and function. In: Branson RD, Peterson BD, Carson KD, eds. Humidification: current therapy and controversy. Respiratory Care Clinics of North America 1998; 4: 261-79.
75. Wilkes AR, Hampson MA, Mecklenburgh JS. A method of testing the compliance of 15 and 22 mm conical connectors on heat and moisture exchangers to ISO 5356-1:1987. Journal of Medical Engineering and Technology 1997; 21: 147-150.
76. Wilkes AR, Mapleson WW. Interference of volatile anaesthetics with infrared analysis of carbon dioxide and nitrous oxide tested in the Dräger Cicero EM using sevoflurane. British Journal of Anaesthesia 1996; 76: 737-9.
77. Wilkes AR, Mapleson WW, Mecklenburgh JS. A novel method of measuring the concentration of anaesthetic vapours using a dew-point hygrometer. Physiological Measurement 1994; 15: 29-39.

CHAPTERS IN BOOKS

1. Wilkes AR. Breathing filters, humidifiers and nebulizers. In: Davey AJ, Diba A, eds. Ward's Anaesthetic Equipment, 6th Edition. Edinburgh: Saunders Elsevier, 2012.